Emerging evidence suggests that ferritin light chain (FTL), ferritin heavy chain 1 (FTH1), and transferrin receptor (TFRC) are involved in iron storage, iron entry, and iron homeostasis [17]
Freezing causes ice crystal formation that mechanically disrupts the peptide structure
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However, the endothelial damage observed in ME/CFS patients does not appear to correlate with the usual markers of endothelial dysfunction seen in cardiovascular disease such as increased levels of symmetric dimethylarginine (SDMA), asymmetric dimethylarginine (ADMA), and high-sensitivity C-reactive protein (hs-CRP), and reduced levels of arginine and homoarginine (311)
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