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Alternatively, this splitting paradigm can be integrated with a lumping perspective that emphasizes a shared feature of impaired mitochondrial biology, which has been documented across a wide range of neurodegenerative disorders, including AD, PD, ALS, and HD (Fig

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This lags behind AST/ALT elevation

Importantly, the animal models treated with the nanoparticles did not show any signs for pain, stress, or discomfort, and did not lose any weight (Fig