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An example of such is the voluntary adjustments made by McNeil, the pharmaceutical producer of the Tylenol brand of APAP, wherein the maximum daily APAP dose was reset from 4000 mg to either 3000 mg per day or 3250 mg per day for consumers taking the 500 mg or 325 mg tablet preparations, respectively

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37 It is important to note that some manufacturers have already updated their labeling to reflect these recommendations, although it is not yet mandatory to do so