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To identify broad-spectrum antiviral targets, we required that the corresponding enzyme was identified as a tier-1 target in at least one cell in each dataset, yielding a total of 254 shared tier-1 targets across all datasets/viruses

Ullah, M., Liu, D.D

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Moderate glutathione synthetase deficiency Patients with the moderate variant usually present in the neonatal period with severe and chronic metabolic acidosis, 5-oxoprolinuria, and mild/moderate hemolytic anemia