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It acts independently of the growth hormone pathway

Once activated, ERK1/2 is transferred to the nucleus, where it phosphorylates transcription factors such as c-Myc and c-Fos, leading to the expression of genes responsible for cellular regulations such as cell proliferation, differentiation, and migration

The maximum dose is 2 mg once a week

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How many total milligrams of retatrutide do I need for a full 16-week escalation