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Antioxidant responses and cellular adjustments to oxidative stress

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Ultimately, implementation of immune-augmenting nutritional supplements within breast cancer care may require personalized approaches taking into consideration tumour subtype, underlying immunologic competency/deficiency, previous treatments received, microbiome profile and comorbid autoimmunity as well as multidisciplinary teamwork to translate promising immunobiologic signals into safe and empirically defined adjuncts to conventional anticancer immunity that are additive rather than counterproductive to patient health (197)

If diarrhoea is accompanied by fever, blood in stools, severe abdominal pain, or dehydration, an infectious or inflammatory cause should be considered and medical attention sought promptly