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Co- supplementation of these nutrients has been shown to promote intracellular glutathione levels

Similarly, the identification of APX gene family in Lycopersicum esculentum revealed the presence of seven APX genes: three cytosolic, two peroxisomal, and two chloroplastic (Najami et al., 2008)

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Mangiferin directly binds to Keap1, activates the downstream Nrf2/SLC7A11/GPX4 pathway, inhibits osteoblast ferroptosis, promotes bone formation and improves osteoporosis in ovariectomized mice and iron overload mice