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It is important to note that organelle-containing erythroid lineage cells can undergo intrinsic [37] and extrinsic apoptosis [38], receptor-interacting serine/threonine-protein kinase 1 (RIPK1)-dependent necroptosis [39], or iron-driven ferroptosis [40]

The ratio of GSH:GSSG (glutathione redox ratio) is a sensitive index of oxidative stress, which can lead to a toxic imbalance between the production and removal of reactive oxygen species (ROS)

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156, 367376.CrossRefGoogle ScholarPubMed Gadhia, MM, Maliszewski, AM, OMeara, MC, et al

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