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J., Tucker, K

If B12 is given without adequate folate, the methylation cycle can become inefficient

Liu Y, Zhu X, Wu C, Lang Y, Zhao W, Li Y

Waltham, MA: Elsevier/AP

This is due to their efficacy in encapsulation, ability to traverse biological membranes, capacity for transporting lipophilic drugs, low cytotoxicity, and suitable size, as highlighted by research findings 15,16,17,18,19,20,21