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These data support an effect of IL-13 to decrease total and reduced GSH through high 15LO1, PEBP1, and GPX4 activity, which is partially compensated by (a) increased expression/activity of SLC7A11 to enhance new intracellular GSH production and (b) increased export of GSSG

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In-vitro data are best treated as mechanism-generating, not efficacy-proving

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Exposure to sunlight will indirectly affect the whitening process since it increases the melanin pigments in the skin, thus, might delay the whitening process