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Alpha-synuclein toxicity in drosophila melanogaster is enhanced by the presence of iron: implications for Parkinsons Disease

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Marginean C, Popescu MS, Vladaia M, Tudorascu D, Pirvu DC, Petrescu F

The proposed mechanism centers on modulation of the nitric oxide system: BPC-157 counteracts L-NAME-induced eNOS blockade in rat models and supports vascular sprouting through VEGFR2 internalization (Hsieh et al., J Mol Med , 2017)