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A procedure called Kasai hepatoportoenterostomy (KPE) that replaces the obliterated extrahepatic bile duct with an intestinal conduit is the first-line treatment to re-establish the bile flow with only 50% success rate ( BA is most likely a clinical phenotype resulting from a number of prenatal or perinatal insults to the hepatobiliary tree, and this disease is underpinned by a number of key pathobiological factors (KPFs) either singly or more often in combinations

Known and novel roles of the MET oncogene in cancer: a coherent approach to targeted therapy

S.SmegoD.LiJ.IshidoyaY.OffeiE.Ruiz CastilloM

However, these studies are still in the preliminary stage, and the specific mechanism of action and effects need further research and validation [91, 103]

Remember that consistency is key, and the most effective approach combines multiple strategies rather than relying on any single intervention