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1ad) but in all thirteen tested cancer cell lines derived from different tissues of origin, e.g., the additional NSCLC cell lines H460, H358, H226, H1650, H2009, DMS114, and the primary NSCLC culture PF139, the additional MPM cell line H2452, the pancreatic ductal carcinoma cell line SU86.86, and the breast adenocarcinoma cell line CAL-85-1 (Supplementary Fig

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The glyoxalase pathway (consisting of glyoxalase I and glyoxalase II enzymes) for detoxification of methylglyoxal, a cytotoxic molecule, also requires GSH in the first reaction step