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The signs which indicate that a person may be addicted or dependent on nicotine are: Inability to stop smoking Continuous urge to smoke throughout the day Experiencing withdrawal symptoms when trying to quit smoking Avoiding social or recreational activities Long-term use of nicotine is associated with a decline in memory and risk of Alzheimers disease

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Along this the value of PI ABS and PI CS were 10 times lower compared to the initial day of exposure than the start day