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cerevisiae in which the ATP consuming glucose-glycogen bypass pathway had been shut-down by deletion of the GBE achieved 3.1-fold higher ATP-generating activity and 1.7-fold higher GSH productivity compared with the control strain [15]

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The IGF-1R is mainly involved in regulation of cell proliferation, antiapoptosis, differentiation and cell motility, whereas IR is mostly of impact for control of glucose uptake and metabolism

In rodent models of alkylating-agent, platinum-compound or radiation injury, systemic or intra-ovarian delivery of MSCs consistently restores oestrous cyclicity, replenishes primordial- and growing-follicle pools, and even supports live births [19,20,21,22,23,24]

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