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The following registers/repositories were searched: ClinicalTrials.gov (searched 09/13/2021), Sigma Repository (searched 09/13/2021), Social Science Research Network (SSRN) (searched 09/13/2021), National Technical Information Service (NTIS) (searched 09/13/2021)

LR3 IGF-1 from the day-10 dose is still active for the first day, and the downstream protein-synthesis signaling continues for some period after

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Telomere elongation has been proposed as a means of extending longevity, but studies have been limited in terms of cell types studied [2, 3]

It did not automatically add it to the approved list