Symptoms often mimic: MS or other neurological disorders Rheumatoid arthritis Chronic pain syndromes (like fibromyalgia) Migraines or cluster headaches Cognitive decline Specific red flags we often see at our naturopathic clinic in Phoenix include: Extreme fatigue after any physical exertion Chronic fatigue without any known cause Chronic skin rashes Lyme disease brain fog or memory lapses Depression, anxiety, new onset OCD or tics POTS MCAS (Mast Cell Activation Syndrome) Joint stiffness or migrating pain Word-finding difficulty Sensitivity to temperature changes or heat intolerance Irritable bowel syndrome, abdominal pain Insomnia Any known history of tick bite or living in water damaged buildings Numbness and tingling, or weakness of extremities Unfortunately, standard Lyme tests often miss the diagnosis
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urology 16, 3543
However, as ME/CFS persists over several years, it is hypothesised that the inflammatory profile (231) and plasma immune signatures change with increasing disease duration (225)
