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RSL3 suppresses viability in thyroid cancer cell lines To determine whether GPX4 inhibition affects tumor cell viability, we treated PTC cells with various concentrations of RSL3 and performed a cellular viability assay

Stem cells have also shown significant benefits in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), which is characterized by degeneration of upper and lower motor neurons, with mesenchymal stem cells possibly delaying progression of this disease and even giving partial recovery of neuron function [112-116]

Here, we summarize the current understanding of cellular and molecular mechanisms involved in tumor angiogenesis and discuss challenges and opportunities associated with vascular targeting

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