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L-citrulline (CIT), recognized as a precursor to nitric oxide (NO), has been demonstrated to enhance endothelial functionality, improve oxygen transport, and increase muscle perfusion, while leucine has been shown to stimulate muscle protein synthesis

al., Three weeks of passive and intervallic heat at high temperatures (1002 C) in a sauna improve acclimation to external heat (422 C) in untrained males, Journal of Thermal Biology, Volume 96, 2021

Since some of the studies on peptides were not completed we dont know if there are contraindications with certain medications

Efficacy and safety of methotrexate combined with low- to moderate-dose corticosteroids for severe alopecia areata