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Summary: As Ozempic becomes a household name in medical weight loss, natural peptide therapies such as BPC-157 and MOTS-c are emerging as promising alternatives

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This study was approved by the local ethics committee

On the other hand, hypoxia-induced vascular endothelial growth factor (VEGF) type 2 receptor (VEGFR-2) pathway activation, increasing permeability in the brain microvascular endothelium by decreasing junctional proteins claudin-5, occludin, and ZO-1 (Castaeda-Cabral et al., 2018)

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