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It also promotes the formation of new blood vessels, a process called angiogenesis, which improves the delivery of oxygen and nutrients to damaged tissues, further speeding up recovery

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These mechanisms connect to physiological outcomes (faster wound healing, improved tendon repair, protection of the gastrointestinal lining), but current understanding is based largely on laboratory and animal studies, with limited confirmation in controlled human trials

Several miRNAs have been found to regulate IGF-1 signaling in skeletal muscle, and these miRs are likely regulated in different pathological conditions and contribute to the development of muscle atrophy