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Neurobiology of learning and memory 100 , 98107, (2013)

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Cardiovascular Disease : Long-term nicotine use contributes to the development of cardiovascular diseases, including heart attacks and strokes, due to its effects on blood pressure and heart rate, as well as the promotion of atherosclerosis (plaque buildup in the arteries)

Bidis had glycerol levels ranging from 0.53 to 2.38 mg/g (median 0.74 mg/g), propylene glycol from 0.00 to 0.15 mg/g (median 0.13 mg/g), and triethylene glycol from 0.00 to 0.07 mg/g (median 0.06 mg/g)