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The expression of HAMP and ferritin L and H subunits was higher in M1 macrophages compared to M2 macrophages, while the expression of ferroportin 1 (FPN) and iron regulatory protein 1/2 was lower, suggesting a greater ability to store iron and a stronger resistance to ferroptosis [79, 80]

By reducing oxidative damage, PQQ may contribute to Long COVID relief and the restoration of cellular function

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Due to the rarity of SSc and the underdiagnosis of SIBO, studies remain small and difficult to generalize

However, it has to be kept in mind that there is an interplay between DNA methylation and chromatin configuration, which is regulated by more processes than just DNMTs