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Most rodent studies used: 10 micrograms/kg 100 micrograms/kg Administration routes varied by study: Intraperitoneal injection Subcutaneous injection Oral administration in drinking water Example reference: Sikiric et al., 2018 These dosages reflect controlled laboratory conditions and are not generalised outside experimental models

It possesses inherent anti-inflammatory and antioxidant properties

Additionally, studies in mice have shown higher liver and kidney expression of Selenop in females than that in males (Schomburg et al., 2007), so SELENOP/LRP8-brain Se uptake pathway may also exert sex-dependence

Mild injection site irritation is common